Prescription retinoid really does work.
As we get older, it takes longer for the skin cells in our face and neck to regenerate. This lack of cell turn over causes our skin to become more prone to damage from environmental stresses. Imperfections such as wrinkles, rough texture, fine lines, etc. become more visible and accelerate.
Store-bought products only help the surface layer of your skin. They don't penetrate to help new skin growth.
Only prescription medication containing retinoids (aka tretinoin) reaches the deep layers of your skin to generate new skin cell growth.